Biochips for Physical Exercise Studies

Physical Exercise for Secondary Osteoporosis

Bone loss caused by an underlying medical illness or associated treatment is often termed secondary osteoporosis and is a growing concern for a variety of patients. Exercise has demonstrated efficacy in maintaining bone health for individuals with age-related osteoporosis and its application to other clinical populations with specific interest in preserving bones is being increasingly explored....

Membrane biochips.

Membrane-bound proteins represent the single most important class of drug targets. This article discusses the issues surrounding fabrication of membrane-protein microarrays by conventional robotic pin printing techniques. Ligand binding selectivity and specificity to G protein-coupled receptor (GPCR) microarrays are presented. The potential applications of these arrays for drug screening are di...

Advocating neuroimaging studies of transmitter release in human physical exercise challenges studies

This perspective attempts to outline the emerging role of positron emission tomography (PET) ligand activation studies in human exercise research. By focusing on the endorphinergic system and its acclaimed role for exercise-induced antinociception and mood enhancement, we like to emphasize the unique potential of ligand PET applied to human athletes for uncovering the neurochemistry of exercise...

Biosensors and Biochips

Placement Algorithm for Flow-Based Microfluidic Biochips

Microfluidic biochips revolutionize biology by placing laboratory functionality on a very small chip. The subject of this thesis is a flow-based biochip, which consists of thin channels in which fluids flow. The basic building block of the chip is a valve, which can direct the flow by blocking or unblocking channels. The valves are combined to create components like switches, mixers, and mul-ti...